rs10920531

Variant in the ADIPOR1 gene (Adiponectin Receptor 1)

rs10920531 is a single nucleotide polymorphism (SNP) in the ADIPOR1 gene, involved in adiponectin signaling. Variants at this position have been studied in relation to immune function, metabolism, and chronic illness.

This page is for educational and informational purposes only. Not a diagnostic tool. Always consult a qualified healthcare provider.

What is the rs10920531 variant?

rs10920531 is a SNP (single nucleotide polymorphism) in the ADIPOR1 (Adiponectin Receptor 1) gene. It belongs to the Metabolic category and is part of the Metabolic Regulation biological cluster. ADIPOR1 encodes adiponectin receptor 1, expressed in muscle, which mediates adiponectin's effects on fatty acid oxidation and insulin sensitivity.

Biological role and pathway

This variant sits within the ADIPOR1 gene, which is involved in the adiponectin signaling pathway. Genes within the Metabolic Regulation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

rs10920531 and Long COVID / ME-CFS research

ADIPOR1 variants may influence metabolic adaptation and anti-inflammatory adiponectin signaling relevant to Long COVID metabolic features.

This information is based on published research and does not constitute medical advice. See references below.

Parent gene: ADIPOR1

rs10920531 is one of 1 known variant in the ADIPOR1 gene. To understand the full biological context of this variant, explore the parent gene page.

View ADIPOR1 gene page →

Conditions studied in relation to rs10920531

Research into ADIPOR1 variants including rs10920531 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include ADIPOR1 and the rs10920531 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions

What is the rs10920531 variant in the ADIPOR1 gene?

rs10920531 is a single nucleotide polymorphism (SNP) located in the ADIPOR1 (Adiponectin Receptor 1) gene, which is involved in adiponectin signaling. ADIPOR1 encodes adiponectin receptor 1, expressed in muscle, which mediates adiponectin's effects on fatty acid oxidation and insulin sensitivity.

How may the rs10920531 variant relate to Long COVID or ME/CFS?

ADIPOR1 variants may influence metabolic adaptation and anti-inflammatory adiponectin signaling relevant to Long COVID metabolic features.

Can a consumer DNA test detect the rs10920531 variant?

Many consumer DNA tests such as 23andMe, AncestryDNA, and MyHeritage genotype common SNPs. ChronicDNA analyses your raw DNA file and reports on variants studied in relation to chronic illness, immune function, and metabolism. This is not a diagnostic service — results are informational and educational only.

Find out if you carry the rs10920531 variant

Upload your DNA data from 23andMe, AncestryDNA, or MyHeritage and receive a personalised report covering >80 genes relevant to Long COVID and ME/CFS.

Get Your Personalised DNA Report

Informational and educational only · Not a diagnostic tool · GDPR compliant

References

The following publications were used in compiling the research context for ADIPOR1 and its variants. This is not an exhaustive literature review.

  • [1]PMID: 33153018
  • [2]Nature Genetics
  • [3]Journal of Clinical Investigation