rs66766036

What is the rs66766036 variant?

rs66766036 is a SNP (single nucleotide polymorphism) in the AR (Androgen Receptor) gene. It belongs to the Hormonal category and is part of the Hormonal Regulation biological cluster. AR encodes the androgen receptor, which mediates testosterone and DHT effects on immune function, muscle, and metabolism.

Biological role and pathway

This variant sits within the AR gene, which is involved in the androgen signaling pathway. Genes within the Hormonal Regulation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: AR

rs66766036 is one of 2 known variants in the AR gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs66766036

Research into AR variants including rs66766036 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include AR and the rs66766036 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Other variants in the AR gene

The following variants in AR are also studied in relation to chronic illness and may be analysed together for a more complete picture.

Frequently asked questions