rs9895052

What is the rs9895052 variant?

rs9895052 is a SNP (single nucleotide polymorphism) in the ATP5B (ATP Synthase F1 Subunit Beta) gene. It belongs to the Mitochondrial category and is part of the Mitochondrial Energy Production & PEM biological cluster. ATP5B encodes the beta catalytic subunit of F1 ATP synthase, containing the catalytic site for ATP hydrolysis and synthesis.

Biological role and pathway

This variant sits within the ATP5B gene, which is involved in the mitochondrial ATP synthesis pathway. Genes within the Mitochondrial Energy Production & PEM cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: ATP5B

rs9895052 is one of 1 known variant in the ATP5B gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs9895052

Research into ATP5B variants including rs9895052 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include ATP5B and the rs9895052 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions