rs2743266

What is the rs2743266 variant?

rs2743266 is a SNP (single nucleotide polymorphism) in the COX7A2 (Cytochrome C Oxidase Subunit 7A2) gene. It belongs to the Mitochondrial category and is part of the Mitochondrial Energy Production & PEM biological cluster. COX7A2 encodes a subunit of cytochrome c oxidase involved in regulating electron transfer efficiency.

Biological role and pathway

This variant sits within the COX7A2 gene, which is involved in the oxidative phosphorylation pathway. Genes within the Mitochondrial Energy Production & PEM cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: COX7A2

rs2743266 is one of 1 known variant in the COX7A2 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs2743266

Research into COX7A2 variants including rs2743266 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include COX7A2 and the rs2743266 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions