rs56061981

What is the rs56061981 variant?

rs56061981 is a SNP (single nucleotide polymorphism) in the CXCL10 (C-X-C Motif Chemokine Ligand 10) gene. It belongs to the Chemokine category and is part of the Cytokines & Immune Signaling biological cluster. CXCL10 encodes IP-10, an interferon-induced chemokine that recruits CXCR3-expressing T cells and NK cells to sites of inflammation.

Biological role and pathway

This variant sits within the CXCL10 gene, which is involved in the interferon-induced chemokine signaling pathway. Genes within the Cytokines & Immune Signaling cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: CXCL10

rs56061981 is one of 3 known variants in the CXCL10 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs56061981

Research into CXCL10 variants including rs56061981 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include CXCL10 and the rs56061981 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Other variants in the CXCL10 gene

The following variants in CXCL10 are also studied in relation to chronic illness and may be analysed together for a more complete picture.

Frequently asked questions