rs763110
Variant in the FASLG gene (Fas Ligand)
rs763110 is a single nucleotide polymorphism (SNP) in the FASLG gene, involved in death receptor / apoptosis induction. Variants at this position have been studied in relation to immune function, metabolism, and chronic illness.
This page is for educational and informational purposes only. Not a diagnostic tool. Always consult a qualified healthcare provider.
What is the rs763110 variant?
rs763110 is a SNP (single nucleotide polymorphism) in the FASLG (Fas Ligand) gene. It belongs to the Immune Signaling category and is part of the Immune System & Inflammation biological cluster. FASLG encodes Fas ligand, expressed on cytotoxic T cells and NK cells, which induces apoptosis in target cells expressing Fas (CD95).
Biological role and pathway
This variant sits within the FASLG gene, which is involved in the death receptor / apoptosis induction pathway. Genes within the Immune System & Inflammation cluster work together to maintain balanced function across interconnected biological systems.
Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.
rs763110 and Long COVID / ME-CFS research
Fas/FasL-mediated apoptosis is important for immune cell cytotoxicity and lymphocyte homeostasis; variants may affect immune cell death regulation and lymphopenia in Long COVID.
This information is based on published research and does not constitute medical advice. See references below.
Parent gene: FASLG
rs763110 is one of 2 known variants in the FASLG gene. To understand the full biological context of this variant, explore the parent gene page.
View FASLG gene page →Conditions studied in relation to rs763110
Research into FASLG variants including rs763110 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.
Genetic insights from DNA data
Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include FASLG and the rs763110 variant.
The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.
Other variants in the FASLG gene
The following variants in FASLG are also studied in relation to chronic illness and may be analysed together for a more complete picture.
Frequently asked questions
What is the rs763110 variant in the FASLG gene?
rs763110 is a single nucleotide polymorphism (SNP) located in the FASLG (Fas Ligand) gene, which is involved in death receptor / apoptosis induction. FASLG encodes Fas ligand, expressed on cytotoxic T cells and NK cells, which induces apoptosis in target cells expressing Fas (CD95).
How may the rs763110 variant relate to Long COVID or ME/CFS?
Fas/FasL-mediated apoptosis is important for immune cell cytotoxicity and lymphocyte homeostasis; variants may affect immune cell death regulation and lymphopenia in Long COVID.
Can a consumer DNA test detect the rs763110 variant?
Many consumer DNA tests such as 23andMe, AncestryDNA, and MyHeritage genotype common SNPs. ChronicDNA analyses your raw DNA file and reports on variants studied in relation to chronic illness, immune function, and metabolism. This is not a diagnostic service — results are informational and educational only.
Find out if you carry the rs763110 variant
Upload your DNA data from 23andMe, AncestryDNA, or MyHeritage and receive a personalised report covering >80 genes relevant to Long COVID and ME/CFS.
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References
The following publications were used in compiling the research context for FASLG and its variants. This is not an exhaustive literature review.
- [1]PMID: 32296168
- [2]Nature Immunology
- [3]Cell Death and Differentiation