rs1048201

What is the rs1048201 variant?

rs1048201 is a SNP (single nucleotide polymorphism) in the FGF2 (Fibroblast Growth Factor 2 (Basic FGF)) gene. It belongs to the Signaling category and is part of the Coagulation & Microcirculation biological cluster. FGF2 encodes basic FGF, a potent angiogenic and tissue repair factor that promotes endothelial cell proliferation.

Biological role and pathway

This variant sits within the FGF2 gene, which is involved in the FGF receptor / angiogenesis / tissue repair pathway. Genes within the Coagulation & Microcirculation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: FGF2

rs1048201 is one of 1 known variant in the FGF2 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs1048201

Research into FGF2 variants including rs1048201 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include FGF2 and the rs1048201 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions