rs2071010

What is the rs2071010 variant?

rs2071010 is a SNP (single nucleotide polymorphism) in the FOLR1 (Folate Receptor Alpha) gene. It belongs to the Metabolic category and is part of the Methylation & Neurotransmitters biological cluster. FOLR1 encodes folate receptor alpha, the high-affinity folate receptor on epithelial cells and choroid plexus that mediates folate cellular uptake.

Biological role and pathway

This variant sits within the FOLR1 gene, which is involved in the folate cellular uptake pathway. Genes within the Methylation & Neurotransmitters cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: FOLR1

rs2071010 is one of 1 known variant in the FOLR1 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs2071010

Research into FOLR1 variants including rs2071010 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include FOLR1 and the rs2071010 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions