rs10071552
Variant in the MET gene (MET Proto-Oncogene Receptor Tyrosine Kinase (HGFR))
rs10071552 is a single nucleotide polymorphism (SNP) in the MET gene, involved in HGF / tissue repair and regeneration. Variants at this position have been studied in relation to immune function, metabolism, and chronic illness.
This page is for educational and informational purposes only. Not a diagnostic tool. Always consult a qualified healthcare provider.
What is the rs10071552 variant?
rs10071552 is a SNP (single nucleotide polymorphism) in the MET (MET Proto-Oncogene Receptor Tyrosine Kinase (HGFR)) gene. It belongs to the Signaling category and is part of the Respiratory & Lung Function biological cluster. MET encodes the HGF receptor (c-Met), which drives cell motility, proliferation, and tissue repair in response to hepatocyte growth factor.
Biological role and pathway
This variant sits within the MET gene, which is involved in the HGF / tissue repair and regeneration pathway. Genes within the Respiratory & Lung Function cluster work together to maintain balanced function across interconnected biological systems.
Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.
rs10071552 and Long COVID / ME-CFS research
MET/HGF signaling is critical for lung repair after injury; variants affecting HGF-mediated tissue regeneration may influence pulmonary recovery and fibrosis in Long COVID.
This information is based on published research and does not constitute medical advice. See references below.
Parent gene: MET
rs10071552 is one of 3 known variants in the MET gene. To understand the full biological context of this variant, explore the parent gene page.
View MET gene page →Conditions studied in relation to rs10071552
Research into MET variants including rs10071552 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.
Genetic insights from DNA data
Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include MET and the rs10071552 variant.
The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.
Other variants in the MET gene
The following variants in MET are also studied in relation to chronic illness and may be analysed together for a more complete picture.
Frequently asked questions
What is the rs10071552 variant in the MET gene?
rs10071552 is a single nucleotide polymorphism (SNP) located in the MET (MET Proto-Oncogene Receptor Tyrosine Kinase (HGFR)) gene, which is involved in HGF / tissue repair and regeneration. MET encodes the HGF receptor (c-Met), which drives cell motility, proliferation, and tissue repair in response to hepatocyte growth factor.
How may the rs10071552 variant relate to Long COVID or ME/CFS?
MET/HGF signaling is critical for lung repair after injury; variants affecting HGF-mediated tissue regeneration may influence pulmonary recovery and fibrosis in Long COVID.
Can a consumer DNA test detect the rs10071552 variant?
Many consumer DNA tests such as 23andMe, AncestryDNA, and MyHeritage genotype common SNPs. ChronicDNA analyses your raw DNA file and reports on variants studied in relation to chronic illness, immune function, and metabolism. This is not a diagnostic service — results are informational and educational only.
Find out if you carry the rs10071552 variant
Upload your DNA data from 23andMe, AncestryDNA, or MyHeritage and receive a personalised report covering >80 genes relevant to Long COVID and ME/CFS.
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References
The following publications were used in compiling the research context for MET and its variants. This is not an exhaustive literature review.
- [1]PMID: 33141942
- [2]Nature Genetics
- [3]Cell