rs41279104

What is the rs41279104 variant?

rs41279104 is a SNP (single nucleotide polymorphism) in the NOS1 (Nitric Oxide Synthase 1 (Neuronal)) gene. It belongs to the Neurotransmitter category and is part of the Autonomic Nervous System biological cluster. NOS1 encodes neuronal NOS (nNOS), which produces nitric oxide in neurons to regulate synaptic transmission and vasodilation.

Biological role and pathway

This variant sits within the NOS1 gene, which is involved in the nitric oxide signaling pathway. Genes within the Autonomic Nervous System cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: NOS1

rs41279104 is one of 2 known variants in the NOS1 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs41279104

Research into NOS1 variants including rs41279104 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include NOS1 and the rs41279104 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Other variants in the NOS1 gene

The following variants in NOS1 are also studied in relation to chronic illness and may be analysed together for a more complete picture.

Frequently asked questions