rs1341239

What is the rs1341239 variant?

rs1341239 is a SNP (single nucleotide polymorphism) in the PRL (Prolactin) gene. It belongs to the Hormonal category and is part of the Hormonal Regulation biological cluster. PRL encodes prolactin, which regulates lactation, reproduction, and importantly acts as an immunostimulatory hormone.

Biological role and pathway

This variant sits within the PRL gene, which is involved in the lactotropic and immunomodulatory signaling pathway. Genes within the Hormonal Regulation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: PRL

rs1341239 is one of 1 known variant in the PRL gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs1341239

Research into PRL variants including rs1341239 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include PRL and the rs1341239 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions