rs3809502

What is the rs3809502 variant?

rs3809502 is a SNP (single nucleotide polymorphism) in the RHEB (Ras Homolog, MTORC1 Binding) gene. It belongs to the Signaling category and is part of the Cellular Signaling biological cluster. RHEB encodes a small GTPase that directly activates mTORC1, translating growth factor and nutrient signals to cell growth responses.

Biological role and pathway

This variant sits within the RHEB gene, which is involved in the mTORC1 activation pathway. Genes within the Cellular Signaling cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: RHEB

rs3809502 is one of 1 known variant in the RHEB gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs3809502

Research into RHEB variants including rs3809502 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include RHEB and the rs3809502 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions