rs2834925

What is the rs2834925 variant?

rs2834925 is a SNP (single nucleotide polymorphism) in the RUNX1 (RUNX Family Transcription Factor 1) gene. It belongs to the Immune Signaling category and is part of the Coagulation & Microcirculation biological cluster. RUNX1 encodes a master hematopoietic transcription factor critical for platelet and T cell development.

Biological role and pathway

This variant sits within the RUNX1 gene, which is involved in the hematopoiesis / platelet development pathway. Genes within the Coagulation & Microcirculation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: RUNX1

rs2834925 is one of 1 known variant in the RUNX1 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs2834925

Research into RUNX1 variants including rs2834925 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include RUNX1 and the rs2834925 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions