rs1567524

What is the rs1567524 variant?

rs1567524 is a SNP (single nucleotide polymorphism) in the SCN8A (Sodium Voltage-Gated Channel Alpha Subunit 8) gene. It belongs to the Neurological category and is part of the Neurological & Cognitive Function biological cluster. SCN8A encodes Nav1.6, a sodium channel widely expressed in neurons that sustains high-frequency firing.

Biological role and pathway

This variant sits within the SCN8A gene, which is involved in the neuronal sodium channel / action potential pathway. Genes within the Neurological & Cognitive Function cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: SCN8A

rs1567524 is one of 1 known variant in the SCN8A gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs1567524

Research into SCN8A variants including rs1567524 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SCN8A and the rs1567524 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions