rs7579
Variant in the SELENOP gene (Selenoprotein P)
rs7579 is a single nucleotide polymorphism (SNP) in the SELENOP gene, involved in selenium transport / antioxidant. Variants at this position have been studied in relation to immune function, metabolism, and chronic illness.
This page is for educational and informational purposes only. Not a diagnostic tool. Always consult a qualified healthcare provider.
What is the rs7579 variant?
rs7579 is a SNP (single nucleotide polymorphism) in the SELENOP (Selenoprotein P) gene. It belongs to the Metabolic category and is part of the Oxidative Stress biological cluster. SELENOP encodes selenoprotein P, the major plasma selenium transport protein that delivers selenium to peripheral tissues.
Biological role and pathway
This variant sits within the SELENOP gene, which is involved in the selenium transport / antioxidant pathway. Genes within the Oxidative Stress cluster work together to maintain balanced function across interconnected biological systems.
Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.
rs7579 and Long COVID / ME-CFS research
Low selenium is associated with worse COVID-19 outcomes; SELENOP variants affecting selenium delivery may influence antioxidant capacity and immune function in Long COVID.
This information is based on published research and does not constitute medical advice. See references below.
Parent gene: SELENOP
rs7579 is one of 1 known variant in the SELENOP gene. To understand the full biological context of this variant, explore the parent gene page.
View SELENOP gene page →Conditions studied in relation to rs7579
Research into SELENOP variants including rs7579 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.
Genetic insights from DNA data
Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SELENOP and the rs7579 variant.
The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.
Frequently asked questions
What is the rs7579 variant in the SELENOP gene?
rs7579 is a single nucleotide polymorphism (SNP) located in the SELENOP (Selenoprotein P) gene, which is involved in selenium transport / antioxidant. SELENOP encodes selenoprotein P, the major plasma selenium transport protein that delivers selenium to peripheral tissues.
How may the rs7579 variant relate to Long COVID or ME/CFS?
Low selenium is associated with worse COVID-19 outcomes; SELENOP variants affecting selenium delivery may influence antioxidant capacity and immune function in Long COVID.
Can a consumer DNA test detect the rs7579 variant?
Many consumer DNA tests such as 23andMe, AncestryDNA, and MyHeritage genotype common SNPs. ChronicDNA analyses your raw DNA file and reports on variants studied in relation to chronic illness, immune function, and metabolism. This is not a diagnostic service — results are informational and educational only.
Find out if you carry the rs7579 variant
Upload your DNA data from 23andMe, AncestryDNA, or MyHeritage and receive a personalised report covering >80 genes relevant to Long COVID and ME/CFS.
Get Your Personalised DNA ReportInformational and educational only · Not a diagnostic tool · GDPR compliant
References
The following publications were used in compiling the research context for SELENOP and its variants. This is not an exhaustive literature review.
- [1]PMID: 34088393
- [2]Nature Genetics
- [3]FASEB Journal