rs9806888

What is the rs9806888 variant?

rs9806888 is a SNP (single nucleotide polymorphism) in the SLC10A2 (Solute Carrier Family 10 Member 2 (ASBT)) gene. It belongs to the Metabolic category and is part of the Metabolic Regulation biological cluster. SLC10A2 encodes the apical sodium-dependent bile acid transporter (ASBT) in the ileum, which reabsorbs conjugated bile acids.

Biological role and pathway

This variant sits within the SLC10A2 gene, which is involved in the intestinal bile acid reabsorption pathway. Genes within the Metabolic Regulation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: SLC10A2

rs9806888 is one of 1 known variant in the SLC10A2 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs9806888

Research into SLC10A2 variants including rs9806888 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SLC10A2 and the rs9806888 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions