rs1829057

What is the rs1829057 variant?

rs1829057 is a SNP (single nucleotide polymorphism) in the SLC1A5 (Solute Carrier Family 1 Member 5 (ASCT2)) gene. It belongs to the Metabolic category and is part of the Metabolic Regulation biological cluster. SLC1A5 encodes ASCT2, the primary transporter for glutamine import into cells, especially immune cells and cancer cells.

Biological role and pathway

This variant sits within the SLC1A5 gene, which is involved in the glutamine transport pathway. Genes within the Metabolic Regulation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: SLC1A5

rs1829057 is one of 1 known variant in the SLC1A5 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs1829057

Research into SLC1A5 variants including rs1829057 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SLC1A5 and the rs1829057 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions