rs841853

Variant in the SLC2A1 gene (Solute Carrier Family 2 Member 1 (GLUT1))

rs841853 is a single nucleotide polymorphism (SNP) in the SLC2A1 gene, involved in basal glucose transport. Variants at this position have been studied in relation to immune function, metabolism, and chronic illness.

This page is for educational and informational purposes only. Not a diagnostic tool. Always consult a qualified healthcare provider.

What is the rs841853 variant?

rs841853 is a SNP (single nucleotide polymorphism) in the SLC2A1 (Solute Carrier Family 2 Member 1 (GLUT1)) gene. It belongs to the Metabolic category and is part of the Metabolic Regulation biological cluster. SLC2A1 encodes GLUT1, the ubiquitous glucose transporter responsible for basal glucose uptake in red blood cells and the blood-brain barrier.

Biological role and pathway

This variant sits within the SLC2A1 gene, which is involved in the basal glucose transport pathway. Genes within the Metabolic Regulation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

rs841853 and Long COVID / ME-CFS research

GLUT1 at the blood-brain barrier is critical for cerebral glucose supply; variants may affect brain glucose metabolism and contribute to Long COVID cognitive symptoms.

This information is based on published research and does not constitute medical advice. See references below.

Parent gene: SLC2A1

rs841853 is one of 1 known variant in the SLC2A1 gene. To understand the full biological context of this variant, explore the parent gene page.

View SLC2A1 gene page →

Conditions studied in relation to rs841853

Research into SLC2A1 variants including rs841853 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SLC2A1 and the rs841853 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions

What is the rs841853 variant in the SLC2A1 gene?

rs841853 is a single nucleotide polymorphism (SNP) located in the SLC2A1 (Solute Carrier Family 2 Member 1 (GLUT1)) gene, which is involved in basal glucose transport. SLC2A1 encodes GLUT1, the ubiquitous glucose transporter responsible for basal glucose uptake in red blood cells and the blood-brain barrier.

How may the rs841853 variant relate to Long COVID or ME/CFS?

GLUT1 at the blood-brain barrier is critical for cerebral glucose supply; variants may affect brain glucose metabolism and contribute to Long COVID cognitive symptoms.

Can a consumer DNA test detect the rs841853 variant?

Many consumer DNA tests such as 23andMe, AncestryDNA, and MyHeritage genotype common SNPs. ChronicDNA analyses your raw DNA file and reports on variants studied in relation to chronic illness, immune function, and metabolism. This is not a diagnostic service — results are informational and educational only.

Find out if you carry the rs841853 variant

Upload your DNA data from 23andMe, AncestryDNA, or MyHeritage and receive a personalised report covering >80 genes relevant to Long COVID and ME/CFS.

Get Your Personalised DNA Report

Informational and educational only · Not a diagnostic tool · GDPR compliant

References

The following publications were used in compiling the research context for SLC2A1 and its variants. This is not an exhaustive literature review.

  • [1]PMID: 33153018
  • [2]Nature Genetics
  • [3]Journal of Clinical Investigation