rs11568350

What is the rs11568350 variant?

rs11568350 is a SNP (single nucleotide polymorphism) in the SLC40A1 (Solute Carrier Family 40 Member 1 (Ferroportin)) gene. It belongs to the Vitamin Metabolism category and is part of the Vitamin & Nutrient Metabolism biological cluster. SLC40A1 encodes ferroportin, the only known cellular iron exporter, regulated by hepcidin to control systemic iron balance.

Biological role and pathway

This variant sits within the SLC40A1 gene, which is involved in the iron export pathway. Genes within the Vitamin & Nutrient Metabolism cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: SLC40A1

rs11568350 is one of 1 known variant in the SLC40A1 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs11568350

Research into SLC40A1 variants including rs11568350 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SLC40A1 and the rs11568350 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions