rs59678213

What is the rs59678213 variant?

rs59678213 is a SNP (single nucleotide polymorphism) in the UGT2B17 (UDP Glucuronosyltransferase Family 2 Member B17) gene. It belongs to the Pharmacogenomics category and is part of the Detox & Medication Sensitivity biological cluster. UGT2B17 encodes a glucuronosyltransferase that conjugates androgens and some NSAIDs for excretion.

Biological role and pathway

This variant sits within the UGT2B17 gene, which is involved in the androgen glucuronidation pathway. Genes within the Detox & Medication Sensitivity cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: UGT2B17

rs59678213 is one of 1 known variant in the UGT2B17 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs59678213

Research into UGT2B17 variants including rs59678213 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include UGT2B17 and the rs59678213 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions