SLC6A19 Gene

What is the SLC6A19 gene?

SLC6A19 encodes solute carrier family 6 member 19 (b0at1), a protein involved in neutral amino acid absorption / tryptophan transport. It belongs to the Metabolic category and is part of the Autonomic Nervous System biological cluster. SLC6A19 encodes B0AT1, a sodium-dependent neutral amino acid transporter in the intestine and kidney that absorbs tryptophan and other neutral amino acids; it co-assembles with ACE2.

Biological role and pathway

SLC6A19 is involved in the neutral amino acid absorption / tryptophan transport pathway, which plays a central role in regulating physiological processes relevant to immune defence, cellular energy, and systemic homeostasis. Genes within the Autonomic Nervous System cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function in these systems — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Known genetic variants

The following variants (SNPs) in the SLC6A19 gene have been studied in relation to metabolic and chronic illness. Each variant represents a single nucleotide position where individuals may carry different alleles.

• rs11591766— SLC6A19 variant
• rs200091038— SLC6A19 variant

Conditions studied in relation to SLC6A19

Research into SLC6A19 variants has explored associations with the following conditions. These are areas of scientific investigation and do not imply that SLC6A19 causes or treats any condition.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SLC6A19 and related genes in the autonomic nervous system pathway.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Related genes in the Autonomic Nervous System pathway

SLC6A19 does not act in isolation. The following genes are functionally related and may be analysed together for a more complete picture of your genetic predispositions.

Frequently asked questions