rs773902

What is the rs773902 variant?

rs773902 is a SNP (single nucleotide polymorphism) in the F2RL3 (Coagulation Factor II Thrombin Receptor Like 3 (PAR4)) gene. It belongs to the Coagulation category and is part of the Coagulation & Microcirculation biological cluster. F2RL3 encodes PAR4, a low-affinity thrombin receptor on platelets and the dominant PAR in Asian platelets.

Biological role and pathway

This variant sits within the F2RL3 gene, which is involved in the thrombin receptor / platelet activation pathway. Genes within the Coagulation & Microcirculation cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: F2RL3

rs773902 is one of 1 known variant in the F2RL3 gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs773902

Research into F2RL3 variants including rs773902 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include F2RL3 and the rs773902 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Frequently asked questions