rs1883965

What is the rs1883965 variant?

rs1883965 is a SNP (single nucleotide polymorphism) in the MTOR (Mechanistic Target of Rapamycin Kinase) gene. It belongs to the Signaling category and is part of the Cellular Signaling biological cluster. MTOR encodes the serine/threonine kinase that integrates nutrient, energy, and growth factor signals to regulate cell growth and autophagy.

Biological role and pathway

This variant sits within the MTOR gene, which is involved in the mTOR signaling pathway. Genes within the Cellular Signaling cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: MTOR

rs1883965 is one of 2 known variants in the MTOR gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs1883965

Research into MTOR variants including rs1883965 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include MTOR and the rs1883965 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Other variants in the MTOR gene

The following variants in MTOR are also studied in relation to chronic illness and may be analysed together for a more complete picture.

Frequently asked questions