rs34713741

What is the rs34713741 variant?

rs34713741 is a SNP (single nucleotide polymorphism) in the SELENOS (Selenoprotein S) gene. It belongs to the Oxidative Stress category and is part of the Oxidative Stress biological cluster. SELENOS encodes selenoprotein S, an ER-resident selenoprotein involved in ER stress responses and inflammatory signaling.

Biological role and pathway

This variant sits within the SELENOS gene, which is involved in the ER stress / selenoprotein pathway. Genes within the Oxidative Stress cluster work together to maintain balanced function across interconnected biological systems.

Variants in genes within this pathway may influence an individual's predisposition to altered function — particularly under conditions of physiological stress such as viral infection or prolonged illness.

Parent gene: SELENOS

rs34713741 is one of 2 known variants in the SELENOS gene. To understand the full biological context of this variant, explore the parent gene page.

Conditions studied in relation to rs34713741

Research into SELENOS variants including rs34713741 has explored associations with the following conditions. These are areas of scientific investigation and do not imply causation.

Genetic insights from DNA data

Consumer DNA files from 23andMe, AncestryDNA, and MyHeritage contain raw SNP data. When you upload your file to ChronicDNA, the analysis engine checks your genotype against a curated panel of 80+ genes selected for their relevance to Long COVID, ME/CFS, and connected biological pathways - some of which may include SELENOS and the rs34713741 variant.

The report is educational - it explains which variants you carry, what the research says about them, and how they fit into the biological pathways most relevant to chronic illness. Results are presented in plain English with appropriate scientific context, no medical jargon, no scare tactics. All results should be discussed with a qualified healthcare provider.

Other variants in the SELENOS gene

The following variants in SELENOS are also studied in relation to chronic illness and may be analysed together for a more complete picture.

Frequently asked questions