Genetic Variants Database

Browse 1258 genetic variants (SNPs) related to Long COVID and ME/CFS, grouped by gene and biological category. Each variant page covers its biological context and relevance to chronic illness research.

Informational and educational purposes only. Not a diagnostic tool.

1258

Total Variants

848

Genes

Acute Phase

1 variants across 1 genes

CRP(1 variant)

rs1205

Adaptive Immunity

27 variants across 11 genes

IKZF3(3 variants)

rs907091 rs2240340 rs2872507

IGHM(2 variants)

rs1136453 rs35000281

BTK(3 variants)

rs1058705 rs33929439 rs13306575

PLCG2(3 variants)

rs72689236 rs3733089 rs3788015

SYK(3 variants)

rs7118 rs37841 rs3176329

EOMES(2 variants)

rs11741861 rs72935865

KLRD1(2 variants)

rs7945685 rs2281052

NKG7(2 variants)

rs11161426 rs12442891

RAB27A(2 variants)

rs6567670 rs2228099

CXCR5(2 variants)

rs630923 rs6421571

CCR2(3 variants)

rs1799864 rs1799865 rs3918358

Antiviral

21 variants across 19 genes

RNASEL(2 variants)

IFIT1(1 variant)

ISG15(1 variant)

USP18(1 variant)

ADAR(1 variant)

EIF2AK2(1 variant)

CGAS(2 variants)

TBK1(1 variant)

MAVS(1 variant)

TREX1(1 variant)

SAMHD1(1 variant)

IKBKE(1 variant)

TMPRSS11D(1 variant)

TMPRSS4(1 variant)

NRP1(1 variant)

NRP2(1 variant)

BSG(1 variant)

PPIA(1 variant)

NLRX1(1 variant)

Autonomic

24 variants across 19 genes

ADRB1(1 variant)

ADRB2(1 variant)

ADRA1A(1 variant)

ACE(1 variant)

NOS3(1 variant)

CHRNA7(1 variant)

AGTR1(2 variants)

OXTR(2 variants)

AVPR1A(1 variant)

NPY(1 variant)

AVP(1 variant)

SLC6A2(2 variants)

GJA5(1 variant)

KCNQ1(2 variants)

SCN5A(2 variants)

KCNMA1(1 variant)

AGTR2(1 variant)

CHRM1(1 variant)

CHRM3(1 variant)

Autophagy

9 variants across 7 genes

BECN1(1 variant)

SQSTM1(1 variant)

ATG5(1 variant)

ATG7(1 variant)

ULK1(1 variant)

ATG16L1(2 variants)

IRGM(2 variants)

Cardiovascular

22 variants across 14 genes

MAS1(1 variant)

REN(2 variants)

AGT(2 variants)

CYP11B2(2 variants)

NR3C2(2 variants)

NOS1AP(2 variants)

HCN4(1 variant)

RYR2(1 variant)

CACNA1C(2 variants)

ADRA2A(1 variant)

CACNB2(2 variants)

SCN3B(1 variant)

KCNH2(2 variants)

KCNJ2(1 variant)

Cell Adhesion

6 variants across 2 genes

ITGA4(3 variants)

rs1143674 rs1456972 rs2254703

SELP(3 variants)

rs6136 rs6138 rs3917884

Chemokine

22 variants across 16 genes

CXCL10(2 variants)

CCL2(2 variants)

CXCL9(1 variant)

CXCL12(1 variant)

CCL5(2 variants)

CCL11(2 variants)

CXCL11(1 variant)

CX3CR1(2 variants)

CCR5(1 variant)

IL8(2 variants)

CXCL1(1 variant)

CXCR3(1 variant)

CXCR4(1 variant)

CCL3(1 variant)

CCL4(1 variant)

CX3CL1(1 variant)

Circadian

14 variants across 9 genes

CLOCK(2 variants)

PER2(2 variants)

ARNTL(2 variants)

CRY1(2 variants)

NR1D1(1 variant)

RORA(1 variant)

CSNK1E(1 variant)

PER1(1 variant)

PER3(2 variants)

Circadian Rhythm

5 variants across 2 genes

BMAL1(3 variants)

rs7107798 rs2278749 rs4757144

CRY2(2 variants)

rs10838524 rs7123390

Coagulation

61 variants across 35 genes

F5(1 variant)

F2(1 variant)

SERPINE1(1 variant)

F13A1(1 variant)

VWF(2 variants)

PLAT(2 variants)

F8(1 variant)

F2R(1 variant)

THBD(1 variant)

PROC(1 variant)

FGA(2 variants)

KLKB1(1 variant)

F12(1 variant)

PLAU(1 variant)

F11(2 variants)

PROS1(1 variant)

TFPI(1 variant)

VKORC1(2 variants)

ADAMTS13(2 variants)

PLG(2 variants)

SERPINE1(2 variants)

GP6(2 variants)

P2RY12(1 variant)

F2RL3(1 variant)

ITGB3(1 variant)

ITGA2(2 variants)

GP1BA(2 variants)

GGCX(3 variants)

rs12714145 rs699664 rs2592551

TBXA2R(3 variants)

rs4523 rs200362481 rs201373570

EPCR(3 variants)

rs867186 rs2069952 rs2069943

SERPINF2(2 variants)

rs2232701 rs2238823

FGB(3 variants)

rs1800790 rs4220 rs2227407

FGG(3 variants)

rs2066865 rs8049607 rs1049636

KNG1(3 variants)

rs5030062 rs710446 rs4253188

F9(3 variants)

rs6048 rs5969474 rs392645

Complement

10 variants across 6 genes

C3(2 variants)

CFH(2 variants)

C5(1 variant)

MBL2(2 variants)

CFB(2 variants)

CR1(1 variant)

Connective Tissue

38 variants across 30 genes

COL1A1(2 variants)

COL3A1(1 variant)

COL5A1(2 variants)

TNXB(2 variants)

FBN1(1 variant)

MMP9(2 variants)

ELN(1 variant)

LOX(1 variant)

MMP2(2 variants)

MMP3(2 variants)

TIMP1(1 variant)

COL6A1(1 variant)

FN1(2 variants)

SPARC(1 variant)

HAS2(1 variant)

HYAL2(1 variant)

ITGB1(1 variant)

ITGAV(1 variant)

CHST3(1 variant)

HSPG2(1 variant)

ACAN(1 variant)

COL2A1(1 variant)

LOXL2(1 variant)

DCN(1 variant)

MMP13(1 variant)

MMP12(1 variant)

ADAMTS5(1 variant)

ACTA2(1 variant)

TAGLN(1 variant)

CDH1(2 variants)

Dna Repair

13 variants across 7 genes

OGG1(1 variant)

BRCA1(2 variants)

ATM(2 variants)

MUTYH(2 variants)

ERCC1(2 variants)

ERCC2(2 variants)

CHEK2(2 variants)

Drug Metabolism

27 variants across 19 genes

CYP1A2(1 variant)

CYP2C19(1 variant)

CYP2D6(1 variant)

CYP3A4(1 variant)

NAT2(1 variant)

UGT1A1(1 variant)

CYP2B6(2 variants)

CYP2C9(2 variants)

ABCB1(2 variants)

SLCO1B1(2 variants)

CYP2E1(2 variants)

ALDH2(1 variant)

ADH1B(2 variants)

ABCG2(2 variants)

CYP4F2(1 variant)

CYP3A5(1 variant)

UGT2B7(1 variant)

SULT1A1(1 variant)

FMO3(2 variants)

Epigenetics

9 variants across 8 genes

SIRT1(2 variants)

DNMT3A(1 variant)

TET2(1 variant)

EZH2(1 variant)

HDAC1(1 variant)

EP300(1 variant)

KAT6A(1 variant)

KDM6A(1 variant)

Genome Stability

17 variants across 8 genes

PARP1(2 variants)

rs1136410 rs3219145

XRCC1(3 variants)

rs25487 rs25489 rs1799782

TP53(2 variants)

rs1042522 rs17878362

MDM2(2 variants)

rs2279744 rs937283

CDKN2A(2 variants)

rs2811712 rs3088440

TERT(3 variants)

rs2736100 rs10069690 rs7726159

TERC(2 variants)

rs10936599 rs12696304

SIRT6(1 variant)

rs107251

Gut Barrier

7 variants across 3 genes

CLDN1(2 variants)

rs17501244 rs2302590

TJP1(3 variants)

rs1784836 rs2189786 rs2291766

REG3A(2 variants)

rs2071659 rs10068546

Gut Microbiome

16 variants across 8 genes

FUT2(2 variants)

LCT(2 variants)

MUC2(1 variant)

DEFB1(2 variants)

CFTR(2 variants)

FFAR2(3 variants)

rs2074056 rs16831294 rs62053150

FFAR3(2 variants)

rs2074058 rs35595281

FFAR4(2 variants)

rs116454156 rs1574941

Histamine

4 variants across 4 genes

DAO(1 variant)

HNMT(1 variant)

HRH1(1 variant)

HRH2(1 variant)

Hormonal

31 variants across 19 genes

ESR1(2 variants)

AR(2 variants)

LEP(2 variants)

LEPR(2 variants)

ADIPOQ(2 variants)

IGF1(2 variants)

CYP17A1(1 variant)

CYP19A1(2 variants)

SHBG(2 variants)

SRD5A1(1 variant)

HSD3B1(1 variant)

GH1(1 variant)

GHR(2 variants)

PRL(1 variant)

TPO(2 variants)

TSHR(2 variants)

TG(1 variant)

DIO1(1 variant)

DIO2(2 variants)

Hpa Axis

13 variants across 7 genes

NR3C1(2 variants)

FKBP5(2 variants)

CRH(2 variants)

CRHR1(2 variants)

HSD11B1(2 variants)

POMC(2 variants)

HSP90AA1(1 variant)

Immune Checkpoint

8 variants across 5 genes

CTLA4(1 variant)

PDCD1(2 variants)

CD274(2 variants)

LAG3(1 variant)

HAVCR2(2 variants)

Immune Presentation

11 variants across 9 genes

HLA-DQA1(1 variant)

HLA-DQB1(1 variant)

HLA-DRB1(1 variant)

HLA-B(1 variant)

HLA-A(2 variants)

HLA-C(1 variant)

B2M(1 variant)

HLA-DRB5(1 variant)

TAP1(2 variants)

Immune Regulation

6 variants across 4 genes

FOXP3(2 variants)

FCGR2A(1 variant)

FCGR3A(1 variant)

ABO(2 variants)

Immune Signaling

178 variants across 131 genes

IL6(1 variant)

IL1B(1 variant)

IL10(1 variant)

TNF(1 variant)

IFNG(1 variant)

STAT3(1 variant)

STAT1(1 variant)

IL7R(1 variant)

IL2RA(1 variant)

TGFB1(1 variant)

IL4(1 variant)

IL13(1 variant)

IL2(2 variants)

IL17A(2 variants)

IL33(2 variants)

IL18(2 variants)

NFKB1(2 variants)

IL12A(1 variant)

IL23A(1 variant)

IL15(1 variant)

IL21(1 variant)

IL22(1 variant)

IL31(1 variant)

TSLP(2 variants)

NOS2(2 variants)

IL6ST(1 variant)

IL10RA(1 variant)

IL17F(2 variants)

IL5(1 variant)

IL9(1 variant)

IL25(1 variant)

IL27(1 variant)

IL37(1 variant)

TNFSF10(1 variant)

CNR2(2 variants)

IL1R1(1 variant)

IL1RN(2 variants)

IL36RN(1 variant)

IL10RB(1 variant)

STAT4(2 variants)

STAT6(2 variants)

STAT5A(1 variant)

LZTFL1(2 variants)

rs73064425 rs10490770

SLC6A20(1 variant)

FYCO1(1 variant)

CXCR6(1 variant)

CCR1(1 variant)

CAMP(1 variant)

SFTPD(2 variants)

SPP1(2 variants)

CD44(1 variant)

IL1RL1(2 variants)

KLRB1(1 variant)

KLRK1(1 variant)

MICA(2 variants)

MICB(1 variant)

GZMB(1 variant)

PRF1(2 variants)

FASLG(2 variants)

FAS(2 variants)

BCL2(2 variants)

CASP4(1 variant)

GSDMD(1 variant)

NLRP1(2 variants)

IL12RB2(2 variants)

IL6R(2 variants)

TBX21(1 variant)

GATA3(2 variants)

RORC(1 variant)

CD40LG(1 variant)

CD40(2 variants)

PRDM1(2 variants)

IRF4(1 variant)

IRF8(1 variant)

SPI1(1 variant)

CSF1R(1 variant)

CSF2(1 variant)

SIGLEC1(1 variant)

CD14(2 variants)

LBP(1 variant)

CD163(1 variant)

MRC1(1 variant)

IL18R1(1 variant)

IL7(2 variants)

IKBKB(1 variant)

RELA(1 variant)

NFKBIA(2 variants)

JUN(1 variant)

TRAC(1 variant)

HLA-G(2 variants)

HLA-E(1 variant)

KLRC1(1 variant)

LILRB1(1 variant)

FCGR2B(2 variants)

C1QA(1 variant)

C4A(1 variant)

C4B(1 variant)

C5AR1(1 variant)

CFI(1 variant)

CD59(1 variant)

SERPING1(1 variant)

PTAFR(1 variant)

PLA2G4A(1 variant)

PTGS1(2 variants)

ALOX12(2 variants)

EPX(1 variant)

ELANE(1 variant)

SERPINA1(2 variants)

CXCL8(2 variants)

CXCR1(1 variant)

IL23R(2 variants)

IL12B(2 variants)

IL4RA(2 variants)

MS4A2(2 variants)

KITLG(2 variants)

CPA3(1 variant)

TREM2(2 variants)

rs75932628 rs143332484

TYROBP(1 variant)

RUNX1(1 variant)

GATA1(1 variant)

KLF1(1 variant)

RIPK3(1 variant)

MLKL(1 variant)

HMGB1(2 variants)

S100A8(1 variant)

S100A9(1 variant)

AGER(2 variants)

CD47(1 variant)

SIRPA(1 variant)

SH2B3(2 variants)

CXCL13(3 variants)

rs355689 rs3769010 rs9943630

Inflammation

7 variants across 3 genes

PTGS2(2 variants)

rs20417 rs689466

ALOX5AP(3 variants)

rs9315052 rs17222919 rs4769055

CYSLTR1(2 variants)

rs321029 rs2637204

Innate Immunity

67 variants across 33 genes

TLR3(1 variant)

rs3775291

TLR7(1 variant)

rs179008

TLR5(1 variant)

rs111200466

NLRP3(2 variants)

rs10754558 rs35829419

NOD2(3 variants)

rs2066844 rs2066845 rs2076756

TLR4(2 variants)

MYD88(1 variant)

IRAK1(1 variant)

IRAK4(1 variant)

P2RX7(2 variants)

CARD9(1 variant)

CASP1(1 variant)

TICAM1(1 variant)

TRAF6(1 variant)

PYCARD(1 variant)

AIM2(1 variant)

DNASE1L3(3 variants)

rs35677470 rs1005753 rs3757247

PAD4(3 variants)

rs2240340 rs874881 rs1748033

CAMP(3 variants)

rs28357093 rs4932015 rs3748082

TLR2(3 variants)

rs5743708 rs3804099 rs4696480

TLR9(3 variants)

rs5743836 rs352139 rs187084

IRF5(4 variants)

rs2004640 rs10954213 rs4728142 rs3807306

UNC93B1(3 variants)

rs35095487 rs9924987 rs6503414

DDX58(3 variants)

rs4497337 rs9695310 rs3205166

TRIM25(3 variants)

rs4803661 rs7218 rs2278677

OASL(2 variants)

rs1169017 rs2285884

BST2(3 variants)

rs3217318 rs1139985 rs2725270

APOBEC3G(2 variants)

rs8177832 rs2010422

TRIM5(3 variants)

rs3740996 rs10838525 rs7948500

LGP2(2 variants)

rs10272618 rs11875065

DDX60(2 variants)

rs17846069 rs6047772

HERC5(2 variants)

rs117854909 rs2290095

CLEC7A(2 variants)

rs16910526 rs2078178

Jak Stat

7 variants across 6 genes

JAK1(1 variant)

JAK2(1 variant)

TYK2(2 variants)

SOCS1(1 variant)

SOCS3(1 variant)

JAK3(1 variant)

Lipid Metabolism

30 variants across 16 genes

APOE(2 variants)

APOE(2 variants)

LDLR(2 variants)

PCSK9(2 variants)

FADS1(2 variants)

FADS2(2 variants)

HMGCR(2 variants)

rs17238484 rs17244841

APOB(2 variants)

APOA1(2 variants)

LPL(2 variants)

CETP(2 variants)

ABCA1(2 variants)

FASN(1 variant)

SCD(1 variant)

SREBF1(2 variants)

PLIN1(2 variants)

Lymphocyte

14 variants across 12 genes

CD4(1 variant)

CD8A(1 variant)

CD19(1 variant)

CD28(1 variant)

LCK(1 variant)

ZAP70(1 variant)

RAG1(1 variant)

MS4A1(1 variant)

BCL6(1 variant)

IKZF1(2 variants)

CD40LG(2 variants)

AICDA(1 variant)

Mast Cell

6 variants across 4 genes

TPSAB1(1 variant)

FCER1A(2 variants)

KIT(1 variant)

ALOX5(2 variants)

Metabolic

116 variants across 82 genes

HIF1A(2 variants)

PPARG(2 variants)

PPARA(2 variants)

INSR(2 variants)

ADIPOR1(1 variant)

NAMPT(2 variants)

PRKAA2(1 variant)

TCF7L2(2 variants)

GCK(2 variants)

INS(2 variants)

SLC2A4(1 variant)

SLC2A1(1 variant)

HK1(1 variant)

LDHA(1 variant)

CYP2R1(2 variants)

DHCR7(2 variants)

PPARD(2 variants)

IDH1(1 variant)

IDH2(1 variant)

SUCLA2(1 variant)

UQCRC1(1 variant)

COX4I1(1 variant)

CYCS(1 variant)

ACO2(1 variant)

CS(1 variant)

FH(1 variant)

PCCA(1 variant)

MUT(1 variant)

MMAB(2 variants)

TYMS(2 variants)

ATIC(1 variant)

CD38(2 variants)

PRKAA1(1 variant)

PPARGC1B(2 variants)

ESRRA(2 variants)

ARG1(2 variants)

CD36(2 variants)

FGF23(2 variants)

APOC3(2 variants)

APOA5(2 variants)

CYP7A1(1 variant)

NR1H4(2 variants)

SLC10A2(1 variant)

SELENOP(1 variant)

SLC7A11(1 variant)

FTH1(1 variant)

FTL(1 variant)

SLC25A37(1 variant)

FECH(1 variant)

EPO(2 variants)

ATP7A(1 variant)

ATP7B(2 variants)

SLC39A8(2 variants)

SLC30A8(1 variant)

HNF1A(2 variants)

HNF4A(2 variants)

ABCC8(2 variants)

KCNJ11(2 variants)

ADRB3(1 variant)

SLC5A1(1 variant)

SLC5A2(1 variant)

ALDOB(1 variant)

G6PC(1 variant)

PCK1(1 variant)

GOT1(1 variant)

GPT(2 variants)

CPS1(1 variant)

GLS(1 variant)

SLC1A5(1 variant)

SLC7A5(1 variant)

SLC6A19(2 variants)

rs11591766 rs200091038

KYNU(1 variant)

SRD5A2(2 variants)

HSD11B2(1 variant)

THPO(1 variant)

HBA1(1 variant)

HBB(2 variants)

PKLR(1 variant)

ABCB11(2 variants)

ABCB4(1 variant)

MTHFS(1 variant)

PDE3B(1 variant)

Metabolism

26 variants across 9 genes

ARNT(2 variants)

rs2228099 rs7165637

EPHX1(3 variants)

rs1051740 rs2234922 rs4653438

AOC1(3 variants)

rs10156191 rs2052129 rs1049742

HDC(3 variants)

rs2071577 rs854144 rs2046631

ANGPTL3(3 variants)

rs10490624 rs2131925 rs12130199

ANGPTL4(3 variants)

rs116843064 rs2278236 rs1044250

LIPC(3 variants)

rs1800588 rs4775041 rs2070895

LCAT(3 variants)

rs4303171 rs5923 rs2292318

NPC1(3 variants)

rs1788822 rs1805081 rs3747178

Methylation

9 variants across 8 genes

MTHFR(2 variants)

MTR(1 variant)

MTRR(1 variant)

BHMT(1 variant)

CBS(1 variant)

COMT(1 variant)

AHCY(1 variant)

MAT1A(1 variant)

Mitochondrial

28 variants across 25 genes

PPARGC1A(1 variant)

NDUFS7(1 variant)

NDUFAF1(1 variant)

COX5A(1 variant)

COX7A2(1 variant)

ATP5F1(1 variant)

UCP2(1 variant)

UCP3(1 variant)

TFAM(1 variant)

POLG(2 variants)

rs113994095 rs1800853

PINK1(2 variants)

rs45478900 rs36228960

PRKN(2 variants)

SIRT3(1 variant)

NDUFV1(1 variant)

SDHA(1 variant)

UQCRC2(1 variant)

ATP5A1(1 variant)

CPT1A(1 variant)

ACADM(1 variant)

HADHA(1 variant)

ACADVL(1 variant)

NDUFA9(1 variant)

ATP5B(1 variant)

SDHB(1 variant)

POLG2(1 variant)

Mitochondrial Dynamics

2 variants across 2 genes

MFN2(1 variant)

rs2236911

DNM1L(1 variant)

rs3816248

Mitophagy

3 variants across 2 genes

BNIP3(1 variant)

rs12721480

PRKN(2 variants)

rs1801474 rs10945614

Neuroendocrine

21 variants across 13 genes

MC4R(2 variants)

RETN(2 variants)

GHRH(1 variant)

IGFBP3(2 variants)

MC1R(3 variants)

rs1805007 rs1805008 rs885479

KL(2 variants)

GCG(1 variant)

GLP1R(2 variants)

GHRL(2 variants)

NTS(1 variant)

VIP(1 variant)

CCK(1 variant)

SST(1 variant)

Neurological

33 variants across 26 genes

CACNA1H(1 variant)

SCN1A(1 variant)

SCN8A(1 variant)

KCNQ2(1 variant)

ATP1A3(1 variant)

ATP2B2(1 variant)

TRPM8(2 variants)

TRPM2(1 variant)

PANX1(1 variant)

RAMP1(1 variant)

TAC1(1 variant)

P2RX4(1 variant)

GFAP(2 variants)

S100B(1 variant)

NEFL(1 variant)

MAPT(2 variants)

SNCA(2 variants)

LRRK2(2 variants)

rs34637584 rs33995883

APP(1 variant)

GRN(2 variants)

CREB1(2 variants)

ARC(1 variant)

HOMER1(1 variant)

GRM5(1 variant)

DLG4(1 variant)

GJA1(1 variant)

Neuroplasticity

14 variants across 9 genes

BDNF(2 variants)

NTRK2(2 variants)

NGF(1 variant)

GDNF(1 variant)

DTNBP1(2 variants)

NRXN1(1 variant)

GRIA2(1 variant)

GRIN2B(2 variants)

SNAP25(2 variants)

Neurotransmitter

45 variants across 31 genes

MAOA(2 variants)

MAOB(1 variant)

SLC6A4(2 variants)

TPH1(2 variants)

DRD2(2 variants)

IDO1(2 variants)

DBH(2 variants)

NOS1(2 variants)

TPH2(2 variants)

DRD4(1 variant)

SLC6A3(2 variants)

IDO2(1 variant)

KMO(1 variant)

TDO2(1 variant)

TH(1 variant)

DDC(1 variant)

GAD1(1 variant)

GAD2(1 variant)

GABRA1(1 variant)

SLC6A1(1 variant)

DRD1(1 variant)

DRD3(1 variant)

DRD5(1 variant)

HTR1A(2 variants)

HTR2A(3 variants)

rs6311 rs6313 rs7997012

HTR3A(2 variants)

HTR4(2 variants)

ACHE(1 variant)

CHAT(1 variant)

SLC5A7(1 variant)

PNMT(1 variant)

Oxidative Stress

40 variants across 31 genes

SOD2(1 variant)

GPX1(1 variant)

CAT(1 variant)

NQO1(1 variant)

GSTM1(1 variant)

GSTT1(1 variant)

SOD1(2 variants)

HMOX1(2 variants)

PRDX1(1 variant)

TXN(1 variant)

NFE2L2(2 variants)

GSTP1(2 variants)

GPX4(1 variant)

TXNRD1(1 variant)

MSRA(1 variant)

GPX3(1 variant)

HMOX2(1 variant)

GCLC(1 variant)

GCLM(1 variant)

GSR(1 variant)

G6PD(2 variants)

PRDX2(1 variant)

PRDX3(1 variant)

TXNRD2(1 variant)

CYBB(1 variant)

NOX4(1 variant)

NCF1(1 variant)

MPO(2 variants)

PON1(3 variants)

rs662 rs854560 rs705379

SELENOS(2 variants)

rs34713741 rs28665122

MT1A(1 variant)

rs11076161

Pain Sensory

28 variants across 18 genes

TRPV1(2 variants)

SCN9A(2 variants)

FAAH(2 variants)

CNR1(2 variants)

TRPA1(2 variants)

rs11988795 rs13255063

TRPV4(2 variants)

P2RX3(1 variant)

SCN10A(2 variants)

CACNA1A(2 variants)

BDKRB2(2 variants)

CALCA(1 variant)

TACR1(1 variant)

BDKRB1(1 variant)

TAC1(1 variant)

OPRM1(2 variants)

OPRD1(1 variant)

MGLL(1 variant)

PIEZO2(1 variant)

Pharmacogenomics

13 variants across 8 genes

SLC22A1(2 variants)

SLC22A2(1 variant)

ABCC2(2 variants)

UGT2B17(1 variant)

NAT1(2 variants)

SULT2A1(1 variant)

CYP1A1(2 variants)

CYP1B1(2 variants)

Respiratory

8 variants across 7 genes

MUC5B(2 variants)

MUC5AC(1 variant)

SFTPC(1 variant)

NKX2-1(1 variant)

FOXA2(1 variant)

ABCA3(1 variant)

DNAI1(1 variant)

Signaling

70 variants across 49 genes

MTOR(2 variants)

PTEN(1 variant)

AKT1(2 variants)

MAPK14(1 variant)

GSK3B(2 variants)

TSC1(1 variant)

RHEB(1 variant)

MAPK8(1 variant)

LRRK2(2 variants)

rs34637584 rs33995883

KRAS(1 variant)

CTNNB1(1 variant)

NOTCH1(1 variant)

NOTCH3(1 variant)

SMAD2(1 variant)

SMAD3(1 variant)

SMAD7(1 variant)

PIK3CA(1 variant)

DUSP1(1 variant)

PTPN2(2 variants)

PTPN22(2 variants)

IGF1R(2 variants)

EPAS1(2 variants)

EGLN1(2 variants)

VHL(1 variant)

FOXO1(1 variant)

FOXO3(3 variants)

rs2802292 rs1268170 rs4946935

WNT5A(1 variant)

HES1(1 variant)

SOX9(1 variant)

AHR(2 variants)

MAPK1(1 variant)

EGFR(2 variants)

ERBB2(2 variants)

MET(3 variants)

rs1621 rs41735 rs10071552

HGF(2 variants)

TGFBR1(2 variants)

TGFBR2(2 variants)

ID3(1 variant)

RAC1(1 variant)

RHOA(1 variant)

ROCK2(1 variant)

MYL9(1 variant)

SNAI1(1 variant)

PDE4B(1 variant)

PDE7A(1 variant)

PRKAR1A(1 variant)

PIK3R1(2 variants)

INPP5D(2 variants)

rs10933431 rs61768452

INPPL1(1 variant)

rs7982

Stress Response

1 variants across 1 genes

HSPA1A(1 variant)

rs1043618

Vascular

22 variants across 16 genes

VEGFA(1 variant)

VEGFB(1 variant)

FGF2(1 variant)

EGF(2 variants)

SELE(2 variants)

ICAM1(2 variants)

VCAM1(1 variant)

PDE5A(1 variant)

PIEZO1(2 variants)

TEK(1 variant)

KDR(2 variants)

CDH5(1 variant)

PECAM1(2 variants)

CLDN5(1 variant)

OCLN(1 variant)

TJP1(1 variant)

Viral Defense

20 variants across 15 genes

OAS1(1 variant)

MX1(1 variant)

IFITM3(2 variants)

IRF3(1 variant)

IRF7(2 variants)

STING1(2 variants)

MB21D1(1 variant)

OAS2(1 variant)

OAS3(1 variant)

MX2(1 variant)

IFNAR1(2 variants)

IFNAR2(1 variant)

IRF9(1 variant)

IFNL1(1 variant)

IFNL3(2 variants)

Viral Entry

8 variants across 4 genes

ACE2(2 variants)

TMPRSS2(2 variants)

FURIN(2 variants)

DPP4(2 variants)

Vitamin Metabolism

20 variants across 15 genes

VDR(2 variants)

CYP27B1(2 variants)

GC(2 variants)

FOLR1(1 variant)

TCN2(1 variant)

CYP24A1(2 variants)

RXRA(1 variant)

SLC19A1(1 variant)

DHFR(1 variant)

HFE(2 variants)

HAMP(1 variant)

TFRC(1 variant)

SLC40A1(1 variant)

SLC11A2(1 variant)

TRPM7(1 variant)

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